SCOPe 2.08: Domain d3kasa2: 3kas A:190-382

Lineage for d3kasa2 (3kas A:190-382)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.8: The 'swivelling' beta/beta/alpha domain [52008] (10 superfamilies)
   3 layers: b/b/a; the central sheet is parallel, and the other one is antiparallel; there are some variations in topology
   this domain is thought to be mobile in most multi-domain proteins known to contain it

4. Superfamily c.8.4: PA domain [52025] (1 family)

5. Family c.8.4.1: PA domain [52026] (2 proteins)

6. Protein Transferrin receptor ectodomain, apical domain [52027] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52028] (4 PDB entries)

8. Domain d3kasa2: 3kas A:190-382 [212266]
   Other proteins in same PDB: d3kasa1, d3kasa3
   automated match to d1de4c2
   complexed with k, nag, po4

Details for d3kasa2

PDB Entry: 3kas, 2.4 Å

PDB Description: machupo virus gp1 bound to human transferrin receptor 1

PDB Compounds: (A:) Transferrin receptor protein 1

SCOPe Domain Sequences for d3kasa2:

Sequence, based on SEQRES records:

>d3kasa2 c.8.4.1 (A:190-382) Transferrin receptor ectodomain, apical domain {Human (Homo sapiens) [TaxId: 9606]}
iqvkdsaqnsviivdkngrlvylvenpggyvayskaatvtgklvhanfgtkkdfedlytp
vngsivivragkitfaekvanaeslnaigvliymdqtkfpivnaelsffghahlgtgdpy
tpgfpsfnhtqfppsrssglpnipvqtisraaaeklfgnmegdcpsdwktdstcrmvtse
sknvkltvsnvlk

Sequence, based on observed residues (ATOM records):

>d3kasa2 c.8.4.1 (A:190-382) Transferrin receptor ectodomain, apical domain {Human (Homo sapiens) [TaxId: 9606]}
iqvkdsaqnsviivdkngrlvylvenpggyvayskaatvtgklvhanfgtkkdfedlytp
vngsivivragkitfaekvanaeslnaigvliymdqtkfpivnaelsffghahlgtgdpy
tpgfpstqfppsrssglpnipvqtisraaaeklfgnmegdcpsdwktdstcrmvtseskn
vkltvsnvlk

Timeline for d3kasa2:

• d3kasa2 first appeared in SCOPe 2.03
  
• d3kasa2 appears in SCOPe 2.07