Lineage for d3k83a_ (3k83 A:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2921622Fold c.117: Amidase signature (AS) enzymes [75303] (1 superfamily)
    possible duplication: the topologies of N- and C-terminal halves are similar; 3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213549A867 (A=10); strands from 5 to 9 are antiparallel to the rest
  4. 2921623Superfamily c.117.1: Amidase signature (AS) enzymes [75304] (1 family) (S)
    automatically mapped to Pfam PF01425
  5. 2921624Family c.117.1.1: Amidase signature (AS) enzymes [75305] (5 proteins)
  6. 2921692Protein automated matches [191046] (2 species)
    not a true protein
  7. 2921693Species Norway rat (Rattus norvegicus) [TaxId:10116] [188885] (20 PDB entries)
  8. 2921704Domain d3k83a_: 3k83 A: [212197]
    automated match to d2wapb_
    complexed with 1do, cl, f27

Details for d3k83a_

PDB Entry: 3k83 (more details), 2.25 Å

PDB Description: crystal structure analysis of a biphenyl/oxazole/carboxypyridine alpha-ketoheterocycle inhibitor bound to a humanized variant of fatty acid amide hydrolase
PDB Compounds: (A:) fatty-acid amide hydrolase 1

SCOPe Domain Sequences for d3k83a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3k83a_ c.117.1.1 (A:) automated matches {Norway rat (Rattus norvegicus) [TaxId: 10116]}
grqkargaatrarqkqrasletmdkavqrfrlqnpdldsealltlpllqlvqklqsgels
peavfftylgkawevnkgtncvtsyltdcetqlsqaprqgllygvpvslkecfsykghds
tlglslnegmpsesdcvvvqvlklqgavpfvhtnvpqsmfsydcsnplfgqtmnpwkssk
spggssggegaligsggsplglgtdiggsirfpsafcgicglkptgnrlsksglkgcvyg
qtavqlslgpmardveslalclkallcehlftldptvpplpfreevyrssrplrvgyyet
dnytmpspamrralietkqrleaaghtlipflpnnipyalevlstgglfsdggrsflqnf
kgdfvdpclgdlililrlpswfkrllslllkplfprlaaflnnmrprsaeklwklqheie
myrqsviaqwkamnldvlltpmlgpaldlntpgratgavsytmlyncldfpagvvpvttv
taeddaqmelykgyfgdiwdiilkkamknsvglpvavqcvalpwqeelclrfmreveqlm
tpqkqp

SCOPe Domain Coordinates for d3k83a_:

Click to download the PDB-style file with coordinates for d3k83a_.
(The format of our PDB-style files is described here.)

Timeline for d3k83a_: