SCOPe 2.07: Domain d3k7fb_: 3k7f B:

Lineage for d3k7fb_ (3k7f B:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.117: Amidase signature (AS) enzymes [75303] (1 superfamily)
   possible duplication: the topologies of N- and C-terminal halves are similar; 3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213549A867 (A=10); strands from 5 to 9 are antiparallel to the rest

4. Superfamily c.117.1: Amidase signature (AS) enzymes [75304] (1 family)
   automatically mapped to Pfam PF01425

5. Family c.117.1.1: Amidase signature (AS) enzymes [75305] (5 protein domains)

6. Protein automated matches [191046] (2 species)
   not a true protein

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [188885] (19 PDB entries)

8. Domain d3k7fb_: 3k7f B: [212195]
   automated match to d2wapb_
   complexed with cl, f2c, na

Details for d3k7fb_

PDB Entry: 3k7f, 1.95 Å

PDB Description: Crystal Structure Analysis of a Phenhexyl/Oxazole/Carboxypyridine alpha-Ketoheterocycle Inhibitor Bound to a Humanized Variant of Fatty Acid Amide Hydrolase'

PDB Compounds: (B:) fatty-acid amide hydrolase 1

SCOPe Domain Sequences for d3k7fb_:

Sequence; same for both SEQRES and ATOM records:

>d3k7fb_ c.117.1.1 (B:) automated matches {Norway rat (Rattus norvegicus) [TaxId: 10116]}
grqkargaatrarqkqrasletmdkavqrfrlqnpdldsealltlpllqlvqklqsgels
peavfftylgkawevnkgtncvtsyltdcetqlsqaprqgllygvpvslkecfsykghds
tlglslnegmpsesdcvvvqvlklqgavpfvhtnvpqsmfsydcsnplfgqtmnpwkssk
spggssggegaligsggsplglgtdiggsirfpsafcgicglkptgnrlsksglkgcvyg
qtavqlslgpmardveslalclkallcehlftldptvpplpfreevyrssrplrvgyyet
dnytmpspamrralietkqrleaaghtlipflpnnipyalevlstgglfsdggrsflqnf
kgdfvdpclgdlililrlpswfkrllslllkplfprlaaflnnmrprsaeklwklqheie
myrqsviaqwkamnldvlltpmlgpaldlntpgratgavsytmlyncldfpagvvpvttv
taeddaqmelykgyfgdiwdiilkkamknsvglpvavqcvalpwqeelclrfmreveqlm
tpqkq

Timeline for d3k7fb_:

• d3k7fb_ first appeared in SCOPe 2.03
  
• d3k7fb_ appears in SCOPe 2.06