SCOPe 2.08: Domain d3k7fa_: 3k7f A:

Lineage for d3k7fa_ (3k7f A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.117: Amidase signature (AS) enzymes [75303] (1 superfamily)
   possible duplication: the topologies of N- and C-terminal halves are similar; 3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213549A867 (A=10); strands from 5 to 9 are antiparallel to the rest

4. Superfamily c.117.1: Amidase signature (AS) enzymes [75304] (1 family)
   automatically mapped to Pfam PF01425

5. Family c.117.1.1: Amidase signature (AS) enzymes [75305] (5 proteins)

6. Protein automated matches [191046] (2 species)
   not a true protein

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [188885] (20 PDB entries)

8. Domain d3k7fa_: 3k7f A: [212194]
   automated match to d2wapb_
   complexed with cl, f2c, na

Details for d3k7fa_

PDB Entry: 3k7f, 1.95 Å

PDB Description: crystal structure analysis of a phenhexyl/oxazole/carboxypyridine alpha-ketoheterocycle inhibitor bound to a humanized variant of fatty acid amide hydrolase'

PDB Compounds: (A:) fatty-acid amide hydrolase 1

SCOPe Domain Sequences for d3k7fa_:

Sequence; same for both SEQRES and ATOM records:

>d3k7fa_ c.117.1.1 (A:) automated matches {Norway rat (Rattus norvegicus) [TaxId: 10116]}
tgrqkargaatrarqkqrasletmdkavqrfrlqnpdldsealltlpllqlvqklqsgel
speavfftylgkawevnkgtncvtsyltdcetqlsqaprqgllygvpvslkecfsykghd
stlglslnegmpsesdcvvvqvlklqgavpfvhtnvpqsmfsydcsnplfgqtmnpwkss
kspggssggegaligsggsplglgtdiggsirfpsafcgicglkptgnrlsksglkgcvy
gqtavqlslgpmardveslalclkallcehlftldptvpplpfreevyrssrplrvgyye
tdnytmpspamrralietkqrleaaghtlipflpnnipyalevlstgglfsdggrsflqn
fkgdfvdpclgdlililrlpswfkrllslllkplfprlaaflnnmrprsaeklwklqhei
emyrqsviaqwkamnldvlltpmlgpaldlntpgratgavsytmlyncldfpagvvpvtt
vtaeddaqmelykgyfgdiwdiilkkamknsvglpvavqcvalpwqeelclrfmreveql
mtp

Timeline for d3k7fa_:

• d3k7fa_ first appeared in SCOPe 2.03
  
• d3k7fa_ appears in SCOPe 2.07