SCOPe 2.03: Domain d3jqcc_: 3jqc C:

Lineage for d3jqcc_ (3jqc C:)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.0: automated matches [191313] (1 protein)
   not a true family

6. Protein automated matches [190069] (159 species)
   not a true protein

7. Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [226760] (13 PDB entries)

8. Domain d3jqcc_: 3jqc C: [212038]
   automated match to d1p33a_
   complexed with ju2, nap

Details for d3jqcc_

PDB Entry: 3jqc, 1.8 Å

PDB Description: Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 2-amino-6-bromo-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (JU2)

PDB Compounds: (C:) pteridine reductase 1

SCOPe Domain Sequences for d3jqcc_:

Sequence, based on SEQRES records:

>d3jqcc_ c.2.1.0 (C:) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvqgdhednsngktvetqva
eligtnaiapflltmsfaqrqkgtnpnctssnlsivnlcdamvdqpcmafslynmgkhal
vgltqsaalelapygirvngvapgvsllpvamgeeekdkwrrkvplgrreasaeqiadav
iflvsgsaqyitgsiikvdgglslvha

Sequence, based on observed residues (ATOM records):

>d3jqcc_ c.2.1.0 (C:) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvgktvetqvaeligtnaia
pflltmsfaqrqssnlsivnlcdamvdqpcmafslynmgkhalvgltqsaalelapygir
vngvapgvsllpvamgeeekdkwrrkvplgrreasaeqiadaviflvsgsaqyitgsiik
vdgglslvha

Timeline for d3jqcc_:

• d3jqcc_ is new in SCOPe 2.03-stable
  
• d3jqcc_ appears in SCOPe 2.04
  
• d3jqcc_ appears in the current release, SCOPe 2.08