Lineage for d3jq8a_ (3jq8 A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2090218Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2090219Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2094257Family c.2.1.0: automated matches [191313] (1 protein)
    not a true family
  6. 2094258Protein automated matches [190069] (238 species)
    not a true protein
  7. 2096341Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [226760] (20 PDB entries)
  8. 2096378Domain d3jq8a_: 3jq8 A: [212020]
    automated match to d1p33a_
    complexed with dtt, dx3, nap

Details for d3jq8a_

PDB Entry: 3jq8 (more details), 1.95 Å

PDB Description: Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 6,7,7-trimethyl-7,8-dihydropteridine-2,4-diamine (DX3)
PDB Compounds: (A:) pteridine reductase 1

SCOPe Domain Sequences for d3jq8a_:

Sequence, based on SEQRES records: (download)

>d3jq8a_ c.2.1.0 (A:) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvqgdhednsngktvetqva
eligtnaiapflltmsfaqrqkgtnpnctssnlsivnlcdamvdqpcmafslynmgkhal
vgltqsaalelapygirvngvapgvsllpvamgeeekdkwrrkvplgrreasaeqiadav
iflvsgsaqyitgsiikvdgglslvha

Sequence, based on observed residues (ATOM records): (download)

>d3jq8a_ c.2.1.0 (A:) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvgktvetqvaeligtnaia
pflltmsfaqrqsnlsivnlcdamvdqpcmafslynmgkhalvgltqsaalelapygirv
ngvapgvsllpamgeeekdkwrrkvplgrreasaeqiadaviflvsgsaqyitgsiikvd
gglslvha

SCOPe Domain Coordinates for d3jq8a_:

Click to download the PDB-style file with coordinates for d3jq8a_.
(The format of our PDB-style files is described here.)

Timeline for d3jq8a_: