SCOPe 2.06: Domain d3jq7b_: 3jq7 B:

Lineage for d3jq7b_ (3jq7 B:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.0: automated matches [191313] (1 protein)
   not a true family

6. Protein automated matches [190069] (239 species)
   not a true protein

7. Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [226760] (20 PDB entries)

8. Domain d3jq7b_: 3jq7 B: [212017]
   automated match to d1p33a_
   complexed with act, dtt, dx2, nap

Details for d3jq7b_

PDB Entry: 3jq7, 1.8 Å

PDB Description: Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 6-phenylpteridine-2,4,7-triamine (DX2)

PDB Compounds: (B:) pteridine reductase 1

SCOPe Domain Sequences for d3jq7b_:

Sequence, based on SEQRES records:

>d3jq7b_ c.2.1.0 (B:) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvqgdhednsngktvetqva
eligtnaiapflltmsfaqrqkgtnpnctssnlsivnlcdamvdqpcmafslynmgkhal
vgltqsaalelapygirvngvapgvsllpvamgeeekdkwrrkvplgrreasaeqiadav
iflvsgsaqyitgsiikvdgglslvha

Sequence, based on observed residues (ATOM records):

>d3jq7b_ c.2.1.0 (B:) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvktvetqvaeligtnaiap
flltmsfaqrqnlsivnlcdamvdqpcmafslynmgkhalvgltqsaalelapygirvng
vapgvsllpvamgeeekdkwrrkvplgrreasaeqiadaviflvsgsaqyitgsiikvdg
glslvha

Timeline for d3jq7b_:

• d3jq7b_ first appeared in SCOPe 2.03
  
• d3jq7b_ appears in SCOPe 2.05
  
• d3jq7b_ appears in SCOPe 2.07
  
• d3jq7b_ appears in the current release, SCOPe 2.08