Lineage for d3is4b3 (3is4 B:358-498)

  1. Root: SCOPe 2.04
  2. 1565955Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1603561Fold c.49: Pyruvate kinase C-terminal domain-like [52934] (2 superfamilies)
    3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145, strand 5 is antiparallel to the rest
  4. 1603562Superfamily c.49.1: PK C-terminal domain-like [52935] (2 families) (S)
  5. 1603563Family c.49.1.1: Pyruvate kinase, C-terminal domain [52936] (1 protein)
    automatically mapped to Pfam PF02887
  6. 1603564Protein Pyruvate kinase, C-terminal domain [52937] (6 species)
  7. 1603652Species Trypanosome (Leishmania mexicana) [TaxId:5665] [52940] (11 PDB entries)
  8. 1603658Domain d3is4b3: 3is4 B:358-498 [211868]
    Other proteins in same PDB: d3is4a1, d3is4a2, d3is4b1, d3is4b2
    automated match to d1pkla3
    complexed with gol, ptk

Details for d3is4b3

PDB Entry: 3is4 (more details), 2.1 Å

PDB Description: crystal structure of leishmania mexicana pyruvate kinase (lmpyk)in complex with 1,3,6,8-pyrenetetrasulfonic acid
PDB Compounds: (B:) pyruvate kinase

SCOPe Domain Sequences for d3is4b3:

Sequence, based on SEQRES records: (download)

>d3is4b3 c.49.1.1 (B:358-498) Pyruvate kinase, C-terminal domain {Trypanosome (Leishmania mexicana) [TaxId: 5665]}
neyvffnsikklqhipmsadeavcssavnsvyetkakamvvlsntgrsarlvakyrpncp
ivcvttrlqtcrqlnitqgvesvffdadklghdegkehrvaagvefakskgyvqtgdycv
vihadhkvkgyanqtrillve

Sequence, based on observed residues (ATOM records): (download)

>d3is4b3 c.49.1.1 (B:358-498) Pyruvate kinase, C-terminal domain {Trypanosome (Leishmania mexicana) [TaxId: 5665]}
neyvffnsikklqhipmsadeavcssavnsvyetkakamvvlsntgrsarlvakyrpncp
ivcvttrlqtcrqlnitqgvesvffdadklghdegkehrvaagvefakskgyvqtgdycv
vihayanqtrillve

SCOPe Domain Coordinates for d3is4b3:

Click to download the PDB-style file with coordinates for d3is4b3.
(The format of our PDB-style files is described here.)

Timeline for d3is4b3: