SCOPe 2.06: Domain d3ilca1: 3ilc A:1-196

Lineage for d3ilca1 (3ilc A:1-196)

1. Root: SCOPe 2.06

2. Class f: Membrane and cell surface proteins and peptides [56835] (59 folds)

3. Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
   multi-helical domains of various folds which is thought to unfold in the membrane

4. Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families)
   PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain

5. Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
   Pfam PF00452

6. Protein Apoptosis regulator Bcl-xL [56856] (3 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [103423] (9 PDB entries)

8. Domain d3ilca1: 3ilc A:1-196 [211819]
   Other proteins in same PDB: d3ilca2
   automated match to d1r2da_
   mutant

Details for d3ilca1

PDB Entry: 3ilc, 1.64 Å

PDB Description: crystal structure of mouse bcl-xl mutant (y101a) at ph 6.0

PDB Compounds: (A:) Bcl-2-like protein 1

SCOPe Domain Sequences for d3ilca1:

Sequence, based on SEQRES records:

>d3ilca1 f.1.4.1 (A:1-196) Apoptosis regulator Bcl-xL {Mouse (Mus musculus) [TaxId: 10090]}
msqsnrelvvdflsyklsqkgyswsqfsdveenrteapeeteaeretpsaingnpswhla
dspavngatghsssldarevipmaavkqalreagdefelrarrafsdltsqlhitpgtay
qsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaswmatylndhlep
wiqenggwdtfvdlyg

Sequence, based on observed residues (ATOM records):

>d3ilca1 f.1.4.1 (A:1-196) Apoptosis regulator Bcl-xL {Mouse (Mus musculus) [TaxId: 10090]}
msqsnrelvvdflsyklsqkgyswsqfspmaavkqalreagdefelrarrafsdltsqlh
itpgtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaswmaty
lndhlepwiqenggwdtfvdlyg

Timeline for d3ilca1:

• d3ilca1 first appeared in SCOPe 2.03, called d3ilca_
  
• d3ilca1 was called d3ilca_ in SCOPe 2.05
  
• d3ilca1 appears in SCOPe 2.07
  
• d3ilca1 appears in the current release, SCOPe 2.08