SCOPe 2.05: Domain d3iiga_: 3iig A:

Lineage for d3iiga_ (3iig A:)

1. Root: SCOPe 2.05

2. Class f: Membrane and cell surface proteins and peptides [56835] (57 folds)

3. Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
   multi-helical domains of various folds which is thought to unfold in the membrane

4. Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families)
   PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain

5. Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
   Pfam PF00452

6. Protein Apoptosis regulator Bcl-xL [56856] (3 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [103423] (9 PDB entries)

8. Domain d3iiga_: 3iig A: [211712]
   automated match to d1r2da_
   mutant

Details for d3iiga_

PDB Entry: 3iig, 2.3 Å

PDB Description: crystal structure of mouse bcl-xl mutant (f105a) at ph 5.0

PDB Compounds: (A:) Bcl-2-like protein 1

SCOPe Domain Sequences for d3iiga_:

Sequence, based on SEQRES records:

>d3iiga_ f.1.4.1 (A:) Apoptosis regulator Bcl-xL {Mouse (Mus musculus) [TaxId: 10090]}
sqsnrelvvdflsyklsqkgyswsqfsdveenrteapeeteaeretpsaingnpswhlad
spavngatghsssldarevipmaavkqalreagdefelryrraasdltsqlhitpgtayq
sfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaswmatylndhlepw
iqenggwdtfvdlyg

Sequence, based on observed residues (ATOM records):

>d3iiga_ f.1.4.1 (A:) Apoptosis regulator Bcl-xL {Mouse (Mus musculus) [TaxId: 10090]}
sqsnrelvvdflsyklsqkgyswsqfpmaavkqalreagdefelryrraasdltsqlhit
pgtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaswmatyln
dhlepwiqenggwdtfvdlyg

Timeline for d3iiga_:

• d3iiga_ first appeared in SCOPe 2.03
  
• d3iiga_ appears in SCOPe 2.04
  
• d3iiga_ appears in SCOPe 2.06
  
• d3iiga_ appears in the current release, SCOPe 2.08