SCOPe 2.05: Domain d3ihfa_: 3ihf A:

Lineage for d3ihfa_ (3ihf A:)

1. Root: SCOPe 2.05

2. Class f: Membrane and cell surface proteins and peptides [56835] (57 folds)

3. Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
   multi-helical domains of various folds which is thought to unfold in the membrane

4. Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families)
   PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain

5. Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
   Pfam PF00452

6. Protein Apoptosis regulator Bcl-xL [56856] (3 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [103423] (9 PDB entries)

8. Domain d3ihfa_: 3ihf A: [211686]
   automated match to d1r2da_
   mutant

Details for d3ihfa_

PDB Entry: 3ihf, 2.28 Å

PDB Description: crystal structure of mouse bcl-xl mutant (r139a) at ph 5.0

PDB Compounds: (A:) Bcl-2-like protein 1

SCOPe Domain Sequences for d3ihfa_:

Sequence, based on SEQRES records:

>d3ihfa_ f.1.4.1 (A:) Apoptosis regulator Bcl-xL {Mouse (Mus musculus) [TaxId: 10090]}
sqsnrelvvdflsyklsqkgyswsqfsdveenrteapeeteaeretpsaingnpswhlad
spavngatghsssldarevipmaavkqalreagdefelryrrafsdltsqlhitpgtayq
sfeqvvnelfrdgvnwgaivaffsfggalcvesvdkemqvlvsriaswmatylndhlepw
iqenggwdtfvdlyg

Sequence, based on observed residues (ATOM records):

>d3ihfa_ f.1.4.1 (A:) Apoptosis regulator Bcl-xL {Mouse (Mus musculus) [TaxId: 10090]}
sqsnrelvvdflsyklsqkgyswsqfsdssldarevipmaavkqalreagdefelryrra
fsdltsqlhitpgtayqsfeqvvnelfrdgvnwgaivaffsfggalcvesvdkemqvlvs
riaswmatylndhlepwiqenggwdtfvdlyg

Timeline for d3ihfa_:

• d3ihfa_ first appeared in SCOPe 2.03
  
• d3ihfa_ appears in SCOPe 2.04
  
• d3ihfa_ appears in SCOPe 2.06
  
• d3ihfa_ appears in the current release, SCOPe 2.08