Lineage for d3i60a_ (3i60 A:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2545120Protein automated matches [190091] (18 species)
    not a true protein
  7. 2545220Species Human (Homo sapiens) [TaxId:9606] [188447] (733 PDB entries)
  8. 2545907Domain d3i60a_: 3i60 A: [211501]
    automated match to d2erka_
    complexed with e86, so4

Details for d3i60a_

PDB Entry: 3i60 (more details), 2.5 Å

PDB Description: crystal structure of erk2 bound to (s)-4-(2-(2-chlorophenylamino)-5- methylpyrimidin-4-yl)-n-(2-hydroxy-1-phenylethyl)-1h-pyrrole-2- carboxamide
PDB Compounds: (A:) Mitogen-activated protein kinase 1

SCOPe Domain Sequences for d3i60a_:

Sequence, based on SEQRES records: (download)

>d3i60a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gagpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqr
tlreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhic
yflyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgfltey
vatrwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgsp
sqedlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqa
lahpyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpgy

Sequence, based on observed residues (ATOM records): (download)

>d3i60a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gagpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqr
tlreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhic
yflyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadatrwyrapeiml
nytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedlnciinlkarny
llslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahpyleqyydpsdep
iaeapfkfdmelddlpkeklkelifeetarfqpgy

SCOPe Domain Coordinates for d3i60a_:

Click to download the PDB-style file with coordinates for d3i60a_.
(The format of our PDB-style files is described here.)

Timeline for d3i60a_: