Lineage for d3i5za_ (3i5z A:)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1929110Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1929111Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1929232Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1931583Protein automated matches [190091] (12 species)
    not a true protein
  7. 1931656Species Human (Homo sapiens) [TaxId:9606] [188447] (553 PDB entries)
  8. 1931962Domain d3i5za_: 3i5z A: [211500]
    automated match to d2erka_
    complexed with so4, z48

Details for d3i5za_

PDB Entry: 3i5z (more details), 2.2 Å

PDB Description: crystal structure of erk2 bound to (s)-n-(2-hydroxy-1-phenylethyl)-4- (5-methyl-2-(phenylamino)pyrimidin-4-yl)-1h-pyrrole-2-carboxamide
PDB Compounds: (A:) Mitogen-activated protein kinase 1

SCOPe Domain Sequences for d3i5za_:

Sequence, based on SEQRES records: (download)

>d3i5za_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gagpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqr
tlreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhic
yflyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgfltey
vatrwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgsp
sqedlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqa
lahpyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpg

Sequence, based on observed residues (ATOM records): (download)

>d3i5za_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gagpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqr
tlreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhic
yflyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvvatrwyrapeimlt
ksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedlnciinlkarnylls
lphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahpyleqyydpsdepiae
apfkfdmelddlpkeklkelifeetarfqpg

SCOPe Domain Coordinates for d3i5za_:

Click to download the PDB-style file with coordinates for d3i5za_.
(The format of our PDB-style files is described here.)

Timeline for d3i5za_: