SCOPe 2.05: Domain d1keml2: 1kem L:113-217

Lineage for d1keml2 (1kem L:113-217)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [88567] (346 PDB entries)
   Uniprot P01837# KAC_MOUSE Ig kappa chain C region; 99% sequence identity ! SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region) ! Uniprot P01837 # KAC_MOUSE Ig kappa chain C region ! Uniprot P01837 # KAC_MOUSE (P01837) Ig kappa chain C region ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01837 # ! KAC_MOUSE Ig kappa chain C region

8. Domain d1keml2: 1kem L:113-217 [21144]
   Other proteins in same PDB: d1kemh1, d1kemh2, d1keml1
   part of Fab 28B4

Details for d1keml2

PDB Entry: 1kem, 2.2 Å

PDB Description: catalytic antibody 28b4 fab fragment

PDB Compounds: (L:) 28b4 fab

SCOPe Domain Sequences for d1keml2:

Sequence; same for both SEQRES and ATOM records:

>d1keml2 b.1.1.2 (L:113-217) Immunoglobulin light chain kappa constant domain, CL-kappa {Mouse (Mus musculus) [TaxId: 10090]}
radaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqd
skdstysmsstltltkdeyerhnsytceathktstspivksfnrn

Timeline for d1keml2:

• d1keml2 first appeared (with stable ids) in SCOP 1.55
  
• d1keml2 appears in SCOPe 2.04
  
• d1keml2 appears in SCOPe 2.06
  
• d1keml2 appears in the current release, SCOPe 2.08