Lineage for d3hrfa_ (3hrf A:)

  1. Root: SCOPe 2.03
  2. 1396887Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1433536Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1433537Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1436359Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 1436360Protein automated matches [190417] (18 species)
    not a true protein
  7. 1436481Species Human (Homo sapiens) [TaxId:9606] [187294] (314 PDB entries)
  8. 1436535Domain d3hrfa_: 3hrf A: [211283]
    automated match to d4eopc_
    complexed with atp, epe, p47

Details for d3hrfa_

PDB Entry: 3hrf (more details), 1.9 Å

PDB Description: crystal structure of human pdk1 kinase domain in complex with an allosteric activator bound to the pif-pocket
PDB Compounds: (A:) 3-phosphoinositide-dependent protein kinase 1

SCOPe Domain Sequences for d3hrfa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3hrfa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtrerdvm
srldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeivsale
ylhgkgiihrdlkpenillnedmhiqitdfgtakvlspeskqaransfvgtaqyvspell
teksackssdlwalgciiyqlvaglppfragneglifakiikleydfpekffpkardlve
kllvldatkrlgceemegygplkahpffesvtwenlhqqtppklt

SCOPe Domain Coordinates for d3hrfa_:

Click to download the PDB-style file with coordinates for d3hrfa_.
(The format of our PDB-style files is described here.)

Timeline for d3hrfa_: