Lineage for d1mrch2 (1mrc H:116-227)

  1. Root: SCOP 1.75
  2. 781541Class b: All beta proteins [48724] (174 folds)
  3. 781542Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 781543Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 783929Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)
  6. 785070Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (7 species)
  7. 785379Species Mouse (Mus musculus) [TaxId:10090] [88576] (373 PDB entries)
    Uniprot P01864 # GCAB_MOUSE Ig gamma-2A chain C region secreted form (B allele)
    Uniprot P01863 #GCAA_MOUSE Ig gamma-2A chain C region, A allele; 86% sequence identity
    SQ NA # natural chimera; best hits are: Uniprot P01751 (Ig heavy chain V region B1-8/186-2) and Uniprot P01864 (Ig gamma-2A chain C region secreted form)
    Uniprot P01868 # GC1_MOUSE Ig gamma-1 chain C region secreted form
    Uniprot P01864 # GCAB_MOUSE (P01864) Ig gamma-2A chain C region
    Uniprot P01837 # KAC_MOUSE (P01837) Ig kappa chain C region
    Uniprot P01863 # GCAA_MOUSE Ig gamma-2A chain C region, A allele
    SQ NA # part of Fab 28 against HIV-1 RT
    Uniprot P01868 #
    GC1_MOUSE Ig gamma-1 chain C region secreted form
    Uniprot P01864 # GCAB_MOUSE Ig gamma-2A chain C region secreted form (B allele) ! Uniprot P01863 #GCAA_MOUSE Ig gamma-2A chain C region, A allele; 86% sequence identity ! SQ NA # natural chimera; best hits are: Uniprot P01751 (Ig heavy chain V region B1-8/186-2) and Uniprot P01864 (Ig gamma-2A chain C region secreted form) ! Uniprot P01868 # GC1_MOUSE Ig gamma-1 chain C region secreted form ! Uniprot P01864 # GCAB_MOUSE (P01864) Ig gamma-2A chain C region ! Uniprot P01837 # KAC_MOUSE (P01837) Ig kappa chain C region ! Uniprot P01863 # GCAA_MOUSE Ig gamma-2A chain C region, A allele ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01868 # ! GC1_MOUSE Ig gamma-1 chain C region secreted form
  8. 785599Domain d1mrch2: 1mrc H:116-227 [21077]
    Other proteins in same PDB: d1mrch1, d1mrcl1, d1mrcl2
    part of Fab Jel 103
    complexed with imd, so4, zn

Details for d1mrch2

PDB Entry: 1mrc (more details), 2.4 Å

PDB Description: preparation, characterization and crystallization of an antibody fab fragment that recognizes rna. crystal structures of native fab and three fab-mononucleotide complexes
PDB Compounds: (H:) igg2b-kappa jel103 fab (heavy chain)

SCOP Domain Sequences for d1mrch2:

Sequence, based on SEQRES records: (download)

>d1mrch2 b.1.1.2 (H:116-227) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Mouse (Mus musculus) [TaxId: 10090]}
ttppsvyplapgcgdttgssvtlgclvkgyfpesvtvtwnsgslsssvhtfpallqsgly
tmsssvtvpsstwpsqtvtcsvahpassttvdkklep

Sequence, based on observed residues (ATOM records): (download)

>d1mrch2 b.1.1.2 (H:116-227) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Mouse (Mus musculus) [TaxId: 10090]}
ttppsvyplapttgssvtlgclvkgyfpesvtvtwnsgslsssvhtfpallqsglytmss
svtvpsstwpsqtvtcsvahpassttvdkklep

SCOP Domain Coordinates for d1mrch2:

Click to download the PDB-style file with coordinates for d1mrch2.
(The format of our PDB-style files is described here.)

Timeline for d1mrch2:

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Domains from same chain:
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d1mrch1