SCOPe 2.04: Domain d3gvua_: 3gvu A:

Lineage for d3gvua_ (3gvu A:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (13 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (490 PDB entries)

8. Domain d3gvua_: 3gvu A: [210687]
   automated match to d1m52b_
   complexed with sti

Details for d3gvua_

PDB Entry: 3gvu, 2.05 Å

PDB Description: the crystal structure of human abl2 in complex with gleevec

PDB Compounds: (A:) Tyrosine-protein kinase ABL2

SCOPe Domain Sequences for d3gvua_:

Sequence, based on SEQRES records:

>d3gvua_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gtenlyfqsmdkwemertditmkhklgggqygevyvgvwkkysltvavktlkedtmevee
flkeaavmkeikhpnlvqllgvctleppfyivteympygnlldylrecnreevtavvlly
matqissameylekknfihrdlaarnclvgenhvvkvadfglsrlmtgdtytahagakfp
ikwtapeslayntfsiksdvwafgvllweiatygmspypgidlsqvydllekgyrmeqpe
gcppkvyelmracwkwspadrpsfaethqafetmfhds

Sequence, based on observed residues (ATOM records):

>d3gvua_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gtenlyfqsmdkwemertditmkhklgggqygevyvgvwkkysltvavktlkedtmevee
flkeaavmkeikhpnlvqllgvctleppfyivteympygnlldylrecnreevtavvlly
matqissameylekknfihrdlaarnclvgenhvvkvadfglsrgdtytakfpikwtape
slayntfsiksdvwafgvllweiatygmspypgidlsqvydllekgyrmeqpegcppkvy
elmracwkwspadrpsfaethqafetmfhds

Timeline for d3gvua_:

• d3gvua_ first appeared in SCOPe 2.03
  
• d3gvua_ appears in SCOPe 2.05
  
• d3gvua_ appears in the current release, SCOPe 2.08, called d3gvua1