SCOPe 2.07: Domain d3gfwa1: 3gfw A:519-794

Lineage for d3gfwa1 (3gfw A:519-794)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (35 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1319 PDB entries)

8. Domain d3gfwa1: 3gfw A:519-794 [210522]
   Other proteins in same PDB: d3gfwa2
   automated match to d2qkra_
   complexed with 7pe, s22

Details for d3gfwa1

PDB Entry: 3gfw, 2.74 Å

PDB Description: Crystal Structure of Human Dual Specificity Protein Kinase (TTK) in complex with a pyrolo-pyridin ligand

PDB Compounds: (A:) Dual specificity protein kinase TTK

SCOPe Domain Sequences for d3gfwa1:

Sequence, based on SEQRES records:

>d3gfwa1 d.144.1.0 (A:519-794) automated matches {Human (Homo sapiens) [TaxId: 9606]}
svkgriysilkqigsggsskvfqvlnekkqiyaikyvnleeadnqtldsyrneiaylnkl
qqhsdkiirlydyeitdqyiymvmecgnidlnswlkkkksidpwerksywknmleavhti
hqhgivhsdlkpanflivdgmlklidfgianqmqpdttsvvkdsqvgtvnymppeaikdm
sssrengkskskispksdvwslgcilyymtygktpfqqiinqisklhaiidpnheiefpd
ipekdlqdvlkcclkrdpkqrisipellahpyvqiq

Sequence, based on observed residues (ATOM records):

>d3gfwa1 d.144.1.0 (A:519-794) automated matches {Human (Homo sapiens) [TaxId: 9606]}
svkgriysilkqigsggsskvfqvlnekkqiyaikyvnleeadnqtldsyrneiaylnkl
qqhsdkiirlydyeitdqyiymvmecgnidlnswlkkkksidpwerksywknmleavhti
hqhgivhsdlkpanflivdgmlklidfgiagtvnymppeaikdskispksdvwslgcily
ymtygktpfqqiinqisklhaiidpnheiefpdipekdlqdvlkcclkrdpkqrisipel
lahpyvqiq

Timeline for d3gfwa1:

• d3gfwa1 first appeared in SCOPe 2.03, called d3gfwa_
  
• d3gfwa1 appears in SCOPe 2.06
  
• d3gfwa1 appears in the current release, SCOPe 2.08