SCOPe 2.08: Domain d3g4na2: 3g4n A:85-467

Lineage for d3g4na2 (3g4n A:85-467)

1. Root: SCOPe 2.08

2. Class f: Membrane and cell surface proteins and peptides [56835] (69 folds)

3. Fold f.8: Aerolisin/ETX pore-forming domain [56972] (1 superfamily)
   3 domains: (1) alpha+beta; (2&3) all-beta

4. Superfamily f.8.1: Aerolisin/ETX pore-forming domain [56973] (3 families)

5. Family f.8.1.1: (Pro)aerolysin, pore-forming lobe [56974] (2 proteins)
   automatically mapped to Pfam PF01117

6. Protein (Pro)aerolysin, pore-forming lobe [56975] (1 species)
   contains the APT module at the N-terminus

7. Species Aeromonas hydrophila [TaxId:644] [56976] (6 PDB entries)

8. Domain d3g4na2: 3g4n A:85-467 [210368]
   Other proteins in same PDB: d3g4na1, d3g4nb1
   automated match to d1z52a2
   mutant

Details for d3g4na2

PDB Entry: 3g4n, 2.1 Å

PDB Description: crystal structure of the activated aerolysin mutant h132d

PDB Compounds: (A:) Aerolysin

SCOPe Domain Sequences for d3g4na2:

Sequence, based on SEQRES records:

>d3g4na2 f.8.1.1 (A:85-467) (Pro)aerolysin, pore-forming lobe {Aeromonas hydrophila [TaxId: 644]}
iptlsaldipdgdevdvqwrlvhdsanfikptsylahylgyawvggndsqyvgedmdvtr
dgdgwvirgnndggcdgyrcgdktaikvsnfaynldpdsfkhgdvtqsdrqlvktvvgwa
vndsdtpqsgydvtlrydtatnwsktntyglsekvttknkfkwplvgetelsieiaanqs
wasqnggstttslsqsvrptvparskipvkielykadisypyefkadvsydltlsgflrw
ggnawythpdnrpnwnhtfvigpykdkassiryqwdkryipgevkwwdwnwtiqqnglst
mqnnlarvlrpvragitgdfsaesqfagnieigapvplaadskvrrarsvdgagqglrle
ipldaqelsglgfnnvslsvtpa

Sequence, based on observed residues (ATOM records):

>d3g4na2 f.8.1.1 (A:85-467) (Pro)aerolysin, pore-forming lobe {Aeromonas hydrophila [TaxId: 644]}
iptlsaldipdgdevdvqwrlvhdsanfikptsylahylgyawvggndsqyvgedmdvtr
dgdgwvirgnndggcdgyrcgdktaikvsnfaynldpdsfkhgdvtqsdrqlvktvvgwa
vndsdtpqsgydvtlrydtatnwsktntyglsekvttknkfkwplvgetelsieiaanqs
wasqnggstttslsqsvrptvparskipvkielykadisypyefkadvsydltlsgflrw
ggnawythpdnrpnwnhtfvigpykdkassiryqwdkryipgevkwwdwnwtiqqnglst
mqnnlarvlrpvragitgdfsaesqfagnieigapvplalrleipldaqelsglgfnnvs
lsvtpa

Timeline for d3g4na2:

• d3g4na2 first appeared in SCOPe 2.03
  
• d3g4na2 appears in SCOPe 2.07