SCOPe 2.03: Domain d3fjca_: 3fjc A:

Lineage for d3fjca_ (3fjc A:)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.42: beta-Trefoil [50352] (8 superfamilies)
   barrel, closed; n=6, S=12; and a hairpin triplet; meander
   duplication: has internal pseudo threefold symmetry

4. Superfamily b.42.1: Cytokine [50353] (3 families)

5. Family b.42.1.1: Fibroblast growth factors (FGF) [50354] (10 proteins)

6. Protein Acidic FGF (FGF1) [50357] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50359] (78 PDB entries)
   Uniprot P05230 16-152 ! Uniprot P05230

8. Domain d3fjca_: 3fjc A: [209961]
   automated match to d1q03a_
   complexed with fmt, so4; mutant

Details for d3fjca_

PDB Entry: 3fjc, 2 Å

PDB Description: crystal structure of l44w mutant of human acidic fibroblast growth factor

PDB Compounds: (A:) heparin-binding growth factor 1

SCOPe Domain Sequences for d3fjca_:

Sequence; same for both SEQRES and ATOM records:

>d3fjca_ b.42.1.1 (A:) Acidic FGF (FGF1) {Human (Homo sapiens) [TaxId: 9606]}
hhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqwqlsaesvgevyi
kstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkngs
ckrgprthygqkailflplpv

Timeline for d3fjca_:

• d3fjca_ is new in SCOPe 2.03-stable
  
• d3fjca_ appears in SCOPe 2.04
  
• d3fjca_ appears in the current release, SCOPe 2.08, called d3fjca1