SCOPe 2.08: Domain d3f6xc_: 3f6x C:

Lineage for d3f6xc_ (3f6x C:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein c-src tyrosine kinase [56155] (3 species)
   PTK group; Src subfamily; non-membrane spanning protein tyrosine kinase

7. Species Chicken (Gallus gallus) [TaxId:9031] [56157] (56 PDB entries)

8. Domain d3f6xc_: 3f6x C: [209816]
   automated match to d2gqgb_
   complexed with ihh

Details for d3f6xc_

PDB Entry: 3f6x, 2.35 Å

PDB Description: c-Src kinase domain in complex with small molecule inhibitor

PDB Compounds: (C:) Proto-oncogene tyrosine-protein kinase Src

SCOPe Domain Sequences for d3f6xc_:

Sequence, based on SEQRES records:

>d3f6xc_ d.144.1.7 (C:) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
lakdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvm
kklrheklvqlyavvseepiyivteymskgslldflkgemgkylrlpqlvdmaaqiasgm
ayvermnyvhrdlraanilvgenlvckvadfglarliedneytarqgakfpikwtapeaa
lygrftiksdvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdl
mcqcwrkdpeerptfeylqafledyftstepqyqpgenl

Sequence, based on observed residues (ATOM records):

>d3f6xc_ d.144.1.7 (C:) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
lakdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkppeaflqeaqvmkklr
heklvqlyavvseepiyivteymskgslldflkgemgkylrlpqlvdmaaqiasgmayve
rmnyvhrdlraanilvgenlvckvadfglarliekfpikwtapeaalygrftiksdvwsf
gilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmcqcwrkdpeerpt
feylqafledyftstepqyqpgenl

Timeline for d3f6xc_:

• d3f6xc_ first appeared in SCOPe 2.03
  
• d3f6xc_ appears in SCOPe 2.07