Lineage for d3exhb1 (3exh B:1-185)

  1. Root: SCOPe 2.03
  2. 1336837Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1361462Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 1361463Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 1362051Family c.36.1.0: automated matches [227300] (1 protein)
    not a true family
  6. 1362052Protein automated matches [227126] (2 species)
    not a true protein
  7. 1362066Species Human (Homo sapiens) [TaxId:9606] [226777] (4 PDB entries)
  8. 1362074Domain d3exhb1: 3exh B:1-185 [209711]
    Other proteins in same PDB: d3exha_, d3exhb2, d3exhc_, d3exhd2, d3exhe_, d3exhf2, d3exhg_, d3exhh2
    automated match to d1umdb1
    complexed with gol, k, mn, tpp

Details for d3exhb1

PDB Entry: 3exh (more details), 2.44 Å

PDB Description: crystal structure of the pyruvate dehydrogenase (e1p) component of human pyruvate dehydrogenase complex
PDB Compounds: (B:) Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

SCOPe Domain Sequences for d3exhb1:

Sequence; same for both SEQRES and ATOM records: (download)

>d3exhb1 c.36.1.0 (B:1-185) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lqvtvrdainqgmdeelerdekvfllgeevaqydgaykvsrglwkkygdkriidtpisem
gfagiavgaamaglrpicefmtfnfsmqaidqvinsaaktyymsgglqpvpivfrgpnga
sagvaaqhsqcfaawyghcpglkvvspwnsedakgliksairdnnpvvvlenelmygvpf
efppe

SCOPe Domain Coordinates for d3exhb1:

Click to download the PDB-style file with coordinates for d3exhb1.
(The format of our PDB-style files is described here.)

Timeline for d3exhb1: