SCOPe 2.04: Domain d3exef2: 3exe F:186-329

Lineage for d3exef2 (3exe F:186-329)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.48: TK C-terminal domain-like [52921] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 13245, strand 1 is antiparallel to the rest

4. Superfamily c.48.1: TK C-terminal domain-like [52922] (4 families)

5. Family c.48.1.2: Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain [52926] (5 proteins)
   automatically mapped to Pfam PF02780

6. Protein E1-beta subunit of pyruvate dehydrogenase, C-domain [69521] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89713] (7 PDB entries)

8. Domain d3exef2: 3exe F:186-329 [209706]
   Other proteins in same PDB: d3exea_, d3exeb1, d3exec_, d3exed1, d3exee_, d3exef1, d3exeg_, d3exeh1
   automated match to d1umdb2
   complexed with gol, k, mn, tpp

Details for d3exef2

PDB Entry: 3exe, 1.98 Å

PDB Description: crystal structure of the pyruvate dehydrogenase (e1p) component of human pyruvate dehydrogenase complex

PDB Compounds: (F:) Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

SCOPe Domain Sequences for d3exef2:

Sequence; same for both SEQRES and ATOM records:

>d3exef2 c.48.1.2 (F:186-329) E1-beta subunit of pyruvate dehydrogenase, C-domain {Human (Homo sapiens) [TaxId: 9606]}
aqskdflipigkakierqgthitvvshsrpvghcleaaavlskegvecevinmrtirpmd
metieasvmktnhlvtveggwpqfgvgaeicarimegpafnfldapavrvtgadvpmpya
kilednsipqvkdiifaikktlni

Timeline for d3exef2:

• d3exef2 first appeared in SCOPe 2.03
  
• d3exef2 appears in SCOPe 2.05
  
• d3exef2 appears in the current release, SCOPe 2.08