Lineage for d1fvea2 (1fve A:108-214)

  1. Root: SCOP 1.63
  2. 218896Class b: All beta proteins [48724] (119 folds)
  3. 218897Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 218898Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 220405Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (9 proteins)
  6. 220881Protein Immunoglobulin (constant domains of L and H chains) [48972] (185 species)
  7. 221789Species Herceptin Fab 4D5 (synthetic, humanised version), kappa L chain [48992] (3 PDB entries)
  8. 221794Domain d1fvea2: 1fve A:108-214 [20966]
    Other proteins in same PDB: d1fvea1, d1fveb1, d1fvec1, d1fved1

Details for d1fvea2

PDB Entry: 1fve (more details), 2.7 Å

PDB Description: x-ray structures of the antigen-binding domains from three variants of humanized anti-p185-her2 antibody 4d5 and comparison with molecular modeling

SCOP Domain Sequences for d1fvea2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1fvea2 b.1.1.2 (A:108-214) Immunoglobulin (constant domains of L and H chains) {Herceptin Fab 4D5 (synthetic, humanised version), kappa L chain}
rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd
skdstyslsstltlskadyekhkvyacevthqglsspvtksfnrgec

SCOP Domain Coordinates for d1fvea2:

Click to download the PDB-style file with coordinates for d1fvea2.
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Timeline for d1fvea2: