SCOP 1.71: Domain d1fvdc2: 1fvd C:108-214

Lineage for d1fvdc2 (1fvd C:108-214)

Root: SCOP 1.71
Class b: All beta proteins [48724] (149 folds)
Fold b.1: Immunoglobulin-like beta-sandwich [48725] (25 superfamilies)
sandwich; 7 strands in 2 sheets; greek-key
some members of the fold have additional strands
Superfamily b.1.1: Immunoglobulin [48726] (4 families)
Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)
Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (3 species)
Species Human (Homo sapiens) [TaxId:9606] [88569] (100 PDB entries)
including humanized antibodies (chimeric proteins with human constant domains)
Domain d1fvdc2: 1fvd C:108-214 [20964]
Other proteins in same PDB: d1fvda1, d1fvdb1, d1fvdb2, d1fvdc1, d1fvdd1, d1fvdd2
part of humanized Fab 4D5, herceptin

Details for d1fvdc2

PDB Entry: 1fvd (more details), 2.5 Å

PDB Description: x-ray structures of the antigen-binding domains from three variants of humanized anti-p185-her2 antibody 4d5 and comparison with molecular modeling

SCOP Domain Sequences for d1fvdc2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1fvdc2 b.1.1.2 (C:108-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens)}
rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd
skdstyslsstltlskadyekhkvyacevthqglsspvtksfnrgec

SCOP Domain Coordinates for d1fvdc2:

Click to download the PDB-style file with coordinates for d1fvdc2.
(The format of our PDB-style files is described here.)

Timeline for d1fvdc2: