Lineage for d1fvdc2 (1fvd C:108-214)

  1. Root: SCOP 1.69
  2. 450777Class b: All beta proteins [48724] (144 folds)
  3. 450778Fold b.1: Immunoglobulin-like beta-sandwich [48725] (23 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 450779Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 452577Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)
  6. 453918Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (3 species)
  7. 453919Species Human (Homo sapiens) [TaxId:9606] [88569] (78 PDB entries)
    including humanized antibodies (chimeric proteins with human constant domains)
  8. 453954Domain d1fvdc2: 1fvd C:108-214 [20964]
    Other proteins in same PDB: d1fvda1, d1fvdb1, d1fvdb2, d1fvdc1, d1fvdd1, d1fvdd2
    part of humanized Fab 4D5, herceptin

Details for d1fvdc2

PDB Entry: 1fvd (more details), 2.5 Å

PDB Description: x-ray structures of the antigen-binding domains from three variants of humanized anti-p185-her2 antibody 4d5 and comparison with molecular modeling

SCOP Domain Sequences for d1fvdc2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1fvdc2 b.1.1.2 (C:108-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens)}
rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd
skdstyslsstltlskadyekhkvyacevthqglsspvtksfnrgec

SCOP Domain Coordinates for d1fvdc2:

Click to download the PDB-style file with coordinates for d1fvdc2.
(The format of our PDB-style files is described here.)

Timeline for d1fvdc2: