SCOPe 2.06: Domain d3ejsa3: 3ejs A:523-1045

Lineage for d3ejsa3 (3ejs A:523-1045)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.30: Supersandwich [49993] (3 superfamilies)
   sandwich; 18 strands in 2 sheets

4. Superfamily b.30.5: Galactose mutarotase-like [74650] (12 families)
   probable carbohydrate-binding domain in enzymes acting on sugars

5. Family b.30.5.6: alpha-mannosidase, C-terminal domain [88656] (2 proteins)
   family 38 glycoside hydrolase; overall domain organization is similar to that of the 4-alpha-glucanotransferase family
   the supersandwich domain is elaborated with additional beta-strands and beta-sandwich subdomains

6. Protein Golgi alpha-mannosidase II [88657] (1 species)

7. Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [88658] (57 PDB entries)
   Uniprot Q24451 94-1107

8. Domain d3ejsa3: 3ejs A:523-1045 [209528]
   Other proteins in same PDB: d3ejsa1, d3ejsa2
   automated match to d1qwna2
   complexed with hn5, mrd, nag, zn

Details for d3ejsa3

PDB Entry: 3ejs, 1.35 Å

PDB Description: golgi alpha-mannosidase ii in complex with 5-substituted swainsonine analog: (5s)-5-[2'-(4-tert-butylphenyl)ethyl]-swainsonine

PDB Compounds: (A:) Alpha-mannosidase 2

SCOPe Domain Sequences for d3ejsa3:

Sequence; same for both SEQRES and ATOM records:

>d3ejsa3 b.30.5.6 (A:523-1045) Golgi alpha-mannosidase II {Fruit fly (Drosophila melanogaster) [TaxId: 7227]}
yftlddsrwpgsgvedsrttiilgedilpskhvvmhntlphwreqlvdfyvsspfvsvtd
lannpveaqvspvwswhhdtltktihpqgsttkyriifkarvppmglatyvltisdskpe
htsyasnlllrknptslplgqypedvkfgdpreislrvgngptlafseqgllksiqltqd
sphvpvhfkflkygvrshgdrsgaylflpngpaspvelgqpvvlvtkgklessvsvglps
vvhqtimrggapeirnlvdigsldnteivmrlethidsgdifytdlnglqfikrrrldkl
plqanyypipsgmfiedantrltlltgqplggsslasgeleimqdrrlasdderglgqgv
ldnkpvlhiyrlvlekvnncvrpsklhpagyltsaahkasqslldpldkfifaenewiga
qgqfggdhpsaredldvsvmrrltkssaktqrvgyvlhrtnlmqcgtpeehtqkldvchl
lpnvarcerttltflqnlehldgmvapevcpmetaayvsshss

Timeline for d3ejsa3:

• d3ejsa3 first appeared in SCOPe 2.03
  
• d3ejsa3 appears in SCOPe 2.05
  
• d3ejsa3 appears in SCOPe 2.07
  
• d3ejsa3 appears in the current release, SCOPe 2.08