SCOPe 2.08: Domain d3e33b_: 3e33 B:

Lineage for d3e33b_ (3e33 B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.102: alpha/alpha toroid [48207] (6 superfamilies)
   multihelical; up to seven alpha-hairpins are arranged in closed circular array; there may be sequence similarities between different superfamilies

4. Superfamily a.102.4: Terpenoid cyclases/Protein prenyltransferases [48239] (5 families)

5. Family a.102.4.3: Protein prenyltransferases [48246] (3 proteins)

6. Protein Protein farnesyltransferase, beta-subunit [48247] (2 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [48248] (50 PDB entries)
   Uniprot Q02293 22-418 P53610

8. Domain d3e33b_: 3e33 B: [209380]
   Other proteins in same PDB: d3e33a_
   automated match to d1d8db_
   complexed with ed7, fpp, zn

Details for d3e33b_

PDB Entry: 3e33, 1.9 Å

PDB Description: Protein farnesyltransferase complexed with FPP and ethylenediamine scaffold inhibitor 7

PDB Compounds: (B:) Protein farnesyltransferase subunit beta

SCOPe Domain Sequences for d3e33b_:

Sequence; same for both SEQRES and ATOM records:

>d3e33b_ a.102.4.3 (B:) Protein farnesyltransferase, beta-subunit {Norway rat (Rattus norvegicus) [TaxId: 10116]}
pvwseplyslrpeharerlqddsvetvtsieqakveekiqevfssykfnhlvprlvlqre
khfhylkrglrqltdayecldasrpwlcywilhslelldepipqivatdvcqflelcqsp
dggfgggpgqyphlaptyaavnalciigteeaynvinrekllqylyslkqpdgsflmhvg
gevdvrsaycaasvasltniitpdlfegtaewiarcqnweggiggvpgmeahggytfcgl
aalvilkkerslnlksllqwvtsrqmrfeggfqgrcnklvdgcysfwqagllpllhralh
aqgdpalsmshwmfhqqalqeyilmccqcpagglldkpgksrdfyhtcyclsglsiaqhf
gsgamlhdvvmgvpenvlqpthpvynigpdkviqatthflqkpvpgf

Timeline for d3e33b_:

• d3e33b_ first appeared in SCOPe 2.03
  
• d3e33b_ appears in SCOPe 2.07