SCOPe 2.05: Domain d3e33a_: 3e33 A:

Lineage for d3e33a_ (3e33 A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (24 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.6: Protein prenylyltransferase [48439] (2 families)

5. Family a.118.6.1: Protein prenylyltransferase [48440] (3 proteins)

6. Protein Protein farnesyltransferase alpha-subunit [48441] (2 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [48442] (51 PDB entries)
   Uniprot Q04631 55-369

8. Domain d3e33a_: 3e33 A: [209379]
   Other proteins in same PDB: d3e33b_
   automated match to d1d8da_
   complexed with ed7, fpp, zn

Details for d3e33a_

PDB Entry: 3e33, 1.9 Å

PDB Description: Protein farnesyltransferase complexed with FPP and ethylenediamine scaffold inhibitor 7

PDB Compounds: (A:) Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

SCOPe Domain Sequences for d3e33a_:

Sequence; same for both SEQRES and ATOM records:

>d3e33a_ a.118.6.1 (A:) Protein farnesyltransferase alpha-subunit {Norway rat (Rattus norvegicus) [TaxId: 10116]}
flsldsptyvlyrdraewadidpvpqndgpspvvqiiysekfrdvydyfravlqrderse
rafkltrdaielnaanytvwhfrrvllrslqkdlqeemnyiiaiieeqpknyqvwhhrrv
lvewlkdpsqelefiadilnqdaknyhawqhrqwviqefrlwdnelqyvdqllkedvrnn
svwnqrhfvisnttgysdravlerevqytlemiklvphnesawnylkgilqdrglsrypn
llnqlldlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirke
ywryigrslqskhsresdipasv

Timeline for d3e33a_:

• d3e33a_ first appeared in SCOPe 2.03
  
• d3e33a_ appears in SCOPe 2.04
  
• d3e33a_ appears in SCOPe 2.06
  
• d3e33a_ appears in the current release, SCOPe 2.08