SCOPe 2.03: Domain d3dooa2: 3doo A:100-267

Lineage for d3dooa2 (3doo A:100-267)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain [51883] (12 proteins)
   extra N-terminal helix displaces the C-terminal helix (following strand 6) from its usual position creating a family nicotineamide-binding site

6. Protein Shikimate 5-dehydrogenase AroE [89538] (6 species)

7. Species Staphylococcus epidermidis [TaxId:176279] [225658] (2 PDB entries)

8. Domain d3dooa2: 3doo A:100-267 [209247]
   Other proteins in same PDB: d3dooa1
   automated match to d1p77a1
   complexed with skm

Details for d3dooa2

PDB Entry: 3doo, 2.2 Å

PDB Description: Crystal structure of shikimate dehydrogenase from Staphylococcus epidermidis complexed with shikimate

PDB Compounds: (A:) Shikimate dehydrogenase

SCOPe Domain Sequences for d3dooa2:

Sequence, based on SEQRES records:

>d3dooa2 c.2.1.7 (A:100-267) Shikimate 5-dehydrogenase AroE {Staphylococcus epidermidis [TaxId: 176279]}
dgigyvnglkqiyegiedayililgaggaskgianelykivrptltvanrtmsrfnnwsl
ninkinlshaeshldefdiiinttpagmngntdsvislnrlashtlvsdivynpyktpil
ieaeqrgnpiyngldmfvhqgaesfkiwtnlepdikamkniviqklkg

Sequence, based on observed residues (ATOM records):

>d3dooa2 c.2.1.7 (A:100-267) Shikimate 5-dehydrogenase AroE {Staphylococcus epidermidis [TaxId: 176279]}
dgigyvnglkqiyegiedayililgaggaskgianelykivrptltvanrtmsrfnnwsl
ninkinlshaeshldefdiiinttpvislnrlashtlvsdivynpyktpilieaeqrgnp
iyngldmfvhqgaesfkiwtnlepdikamkniviqklkg

Timeline for d3dooa2:

• d3dooa2 is new in SCOPe 2.03-stable
  
• d3dooa2 appears in SCOPe 2.04
  
• d3dooa2 appears in the current release, SCOPe 2.08