SCOPe 2.08: Domain d3dona2: 3don A:100-269

Lineage for d3dona2 (3don A:100-269)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain [51883] (12 proteins)
   extra N-terminal helix displaces the C-terminal helix (following strand 6) from its usual position creating a family nicotineamide-binding site

6. Protein Shikimate 5-dehydrogenase AroE [89538] (6 species)

7. Species Staphylococcus epidermidis [TaxId:176279] [225658] (2 PDB entries)

8. Domain d3dona2: 3don A:100-269 [209245]
   Other proteins in same PDB: d3dona1, d3dona3
   automated match to d1p77a1
   complexed with gol

Details for d3dona2

PDB Entry: 3don, 2.1 Å

PDB Description: Crystal structure of shikimate dehydrogenase from Staphylococcus epidermidis

PDB Compounds: (A:) Shikimate dehydrogenase

SCOPe Domain Sequences for d3dona2:

Sequence, based on SEQRES records:

>d3dona2 c.2.1.7 (A:100-269) Shikimate 5-dehydrogenase AroE {Staphylococcus epidermidis [TaxId: 176279]}
dgigyvnglkqiyegiedayililgaggaskgianelykivrptltvanrtmsrfnnwsl
ninkinlshaeshldefdiiinttpagmngntdsvislnrlashtlvsdivynpyktpil
ieaeqrgnpiyngldmfvhqgaesfkiwtnlepdikamkniviqklkgel

Sequence, based on observed residues (ATOM records):

>d3dona2 c.2.1.7 (A:100-269) Shikimate 5-dehydrogenase AroE {Staphylococcus epidermidis [TaxId: 176279]}
dgigyvnglkqiyegiedayililgaggaskgianelykivrptltvanrtmsrfnnwsl
ninkinlshaeshldefdiiinttpdsvislnrlashtlvsdivynpyktpilieaeqrg
npiyngldmfvhqgaesfkiwtnlepdikamkniviqklkgel

Timeline for d3dona2:

• d3dona2 first appeared in SCOPe 2.03
  
• d3dona2 appears in SCOPe 2.07