SCOPe 2.04: Domain d3dc2b3: 3dc2 B:317-451

Lineage for d3dc2b3 (3dc2 B:317-451)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.81: FwdE/GAPDH domain-like [55346] (4 superfamilies)
   core: alpha-beta-alpha-beta(3); mixed sheet: 2134, strand 2 is parallel to strand 1

4. Superfamily d.81.2: Serine metabolism enzymes domain [143548] (2 families)
   contains extra C-terminal beta-hairpin

5. Family d.81.2.2: SerA intervening domain-like [143552] (1 protein)
   PfamB PB001360; this domain is found in some but not all D-3-phosphoglycerate dehydrogenases (SerA) and related enzymes

6. Protein D-3-phosphoglycerate dehydrogenase SerA [143553] (1 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [143554] (2 PDB entries)
   Uniprot P0A544 316-450

8. Domain d3dc2b3: 3dc2 B:317-451 [209077]
   Other proteins in same PDB: d3dc2a1, d3dc2a2, d3dc2a4, d3dc2b1, d3dc2b2, d3dc2b4
   automated match to d1ygya4
   complexed with ser, tla

Details for d3dc2b3

PDB Entry: 3dc2, 2.7 Å

PDB Description: Crystal structure of serine bound D-3-phosphoglycerate dehydrogenase from Mycobacterium tuberculosis

PDB Compounds: (B:) D-3-phosphoglycerate dehydrogenase

SCOPe Domain Sequences for d3dc2b3:

Sequence, based on SEQRES records:

>d3dc2b3 d.81.2.2 (B:317-451) D-3-phosphoglycerate dehydrogenase SerA {Mycobacterium tuberculosis [TaxId: 1773]}
ggvvneevapwldlvrklgvlagvlsdelpvslsvqvrgelaaeevevlrlsalrglfsa
viedavtfvnapalaaergvtaeickasespnhrsvvdvravgadgsvvtvsgtlygpql
sqkivqingrhfdlr

Sequence, based on observed residues (ATOM records):

>d3dc2b3 d.81.2.2 (B:317-451) D-3-phosphoglycerate dehydrogenase SerA {Mycobacterium tuberculosis [TaxId: 1773]}
ggvvneevapwldlvrklgvlagvlsdelpvslsvqvrgelaaeevevlrlsalrglfsa
vietfvnapalaaergvtaeickasespnhrsvvdvravgadgsvvtvsgtlygpqlsqk
ivqingrhfdlr

Timeline for d3dc2b3:

• d3dc2b3 first appeared in SCOPe 2.03
  
• d3dc2b3 appears in SCOPe 2.05
  
• d3dc2b3 appears in the current release, SCOPe 2.08