Lineage for d3d4qb_ (3d4q B:)

  1. Root: SCOPe 2.03
  2. 1396887Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1433536Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1433537Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1433619Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1435613Protein automated matches [190091] (11 species)
    not a true protein
  7. 1435681Species Human (Homo sapiens) [TaxId:9606] [188447] (418 PDB entries)
  8. 1436174Domain d3d4qb_: 3d4q B: [208998]
    automated match to d1i44a_
    complexed with sm5

Details for d3d4qb_

PDB Entry: 3d4q (more details), 2.8 Å

PDB Description: pyrazole-based inhibitors of b-raf kinase
PDB Compounds: (B:) B-Raf proto-oncogene serine/threonine-protein kinase

SCOPe Domain Sequences for d3d4qb_:

Sequence, based on SEQRES records: (download)

>d3d4qb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ddweipdgqitvgqrigsgsfgtvykgkwhgdvavkmlnvtaptpqqlqafknevgvlrk
trhvnillfmgystkpqlaivtqwcegsslyhhlhiietkfemiklidiarqtaqgmdyl
haksiihrdlksnniflhedltvkigdfglatvksrwsgshqfeqlsgsilwmapevirm
qdknpysfqsdvyafgivlyelmtgqlpysninnrdqiifmvgrgylspdlskvrsncpk
amkrlmaeclkkkrderplfpqilasiellarslpk

Sequence, based on observed residues (ATOM records): (download)

>d3d4qb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ddweipdgqitvgqrigsgsfgtvykgkwhgdvavkmlnvtaptpqqlqafknevgvlrk
trhvnillfmgystkpqlaivtqwcegsslyhhlhiietkfemiklidiarqtaqgmdyl
haksiihrdlksnniflhedltvkigdfglatvlsgsilwmapevirmqdknpysfqsdv
yafgivlyelmtgqlpysninnrdqiifmvgrgylspdlskvrsncpkamkrlmaeclkk
krderplfpqilasiellarslpk

SCOPe Domain Coordinates for d3d4qb_:

Click to download the PDB-style file with coordinates for d3d4qb_.
(The format of our PDB-style files is described here.)

Timeline for d3d4qb_: