SCOPe 2.05: Domain d3a74b2: 3a74 B:146-492

Lineage for d3a74b2 (3a74 B:146-492)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.104: Class II aaRS and biotin synthetases [55680] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.104.1: Class II aaRS and biotin synthetases [55681] (5 families)

5. Family d.104.1.1: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain [55682] (16 proteins)

6. Protein Lysyl-tRNA synthetase (LysRS) [55685] (3 species)
   contains an insertion of LEM/SAP-like HeH motif, residues 337-379

7. Species Geobacillus stearothermophilus [TaxId:1422] [225969] (1 PDB entry)

8. Domain d3a74b2: 3a74 B:146-492 [208136]
   Other proteins in same PDB: d3a74a1, d3a74b1, d3a74c1, d3a74d1
   automated match to d1bbua2
   protein/RNA complex; complexed with b4p, lyn, mg

Details for d3a74b2

PDB Entry: 3a74, 1.8 Å

PDB Description: Lysyl-tRNA synthetase from Bacillus stearothermophilus complexed with Diadenosine Tetraphosphate (AP4A)

PDB Compounds: (B:) lysyl-tRNA synthetase

SCOPe Domain Sequences for d3a74b2:

Sequence, based on SEQRES records:

>d3a74b2 d.104.1.1 (B:146-492) Lysyl-tRNA synthetase (LysRS) {Geobacillus stearothermophilus [TaxId: 1422]}
kyhglkdieqryrqryldlimnpeskktfitrsliiqsmrryldshgylevetpmmhava
ggaaarpfithhnaldmtlymriaielhlkrlivgglekvyeigrvfrnegistrhnpef
tmlelyeayadfrdimkltenliahiatevlgttkiqygehlvdltpewrrlhmvdaike
yvgvdfwrqmsdeearelakehgvevaphmtfghivneffeqkvedkliqptfiyghpve
isplakknpddprftdrfelfivgrehanaftelndpidqrqrfeeqlkereqgndeahe
mdedflealeygmpptgglgigvdrlvmlltnspsirdvllfpqmrh

Sequence, based on observed residues (ATOM records):

>d3a74b2 d.104.1.1 (B:146-492) Lysyl-tRNA synthetase (LysRS) {Geobacillus stearothermophilus [TaxId: 1422]}
kdieqryrqryldlimnpeskktfitrsliiqsmrryldshgylevetpmmhavaggaaa
rpfithhnaldmtlymriaielhlkrlivgglekvyeigrvfrnegistrhnpeftmlel
yeayadfrdimkltenliahiatevlgttkiqygehlvdltpewrrlhmvdaikeyvgvd
fwrqmsdeearelakehgvevaphmtfghivneffeqkvedkliqptfiyghpveispla
kknpddprftdrfelfivgrehanaftelndpidqrqrfeeqlkereqgndeahemdedf
lealeygmpptgglgigvdrlvmlltnspsirdvllfpqmrh

Timeline for d3a74b2:

• d3a74b2 first appeared in SCOPe 2.03
  
• d3a74b2 appears in SCOPe 2.04
  
• d3a74b2 appears in SCOPe 2.06
  
• d3a74b2 appears in the current release, SCOPe 2.08