SCOPe 2.07: Domain d2yngb_: 2yng B:

Lineage for d2yngb_ (2yng B:)

1. Root: SCOPe 2.07

2. Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (8 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)

6. Protein automated matches [190211] (7 species)
   not a true protein

7. Species Hiv-1 m:b_hxb2r [TaxId:11706] [187165] (10 PDB entries)

8. Domain d2yngb_: 2yng B: [207674]
   Other proteins in same PDB: d2ynga2, d2ynga3
   automated match to d1hqeb_
   complexed with mg, srt, whu

Details for d2yngb_

PDB Entry: 2yng, 2.12 Å

PDB Description: HIV-1 Reverse Transcriptase in complex with inhibitor GSK560

PDB Compounds: (B:) p51 RT

SCOPe Domain Sequences for d2yngb_:

Sequence, based on SEQRES records:

>d2yngb_ e.8.1.2 (B:) automated matches {Hiv-1 m:b_hxb2r [TaxId: 11706]}
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedf
rkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqym
ddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpi
vlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelela
enreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtnd
vkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvk
lwyq

Sequence, based on observed residues (ATOM records):

>d2yngb_ e.8.1.2 (B:) automated matches {Hiv-1 m:b_hxb2r [TaxId: 11706]}
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedf
rkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqym
ddlyvgsdleigqhrtkieelrqhllrwglttppflwmgyelhpdkwtvqpivlpekdsw
tvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilke
pvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyartndvkqlteavqkitt
esiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq

Timeline for d2yngb_:

• d2yngb_ first appeared in SCOPe 2.03
  
• d2yngb_ appears in SCOPe 2.06
  
• d2yngb_ appears in the current release, SCOPe 2.08