SCOPe 2.08: Domain d2ykmb_: 2ykm B:

Lineage for d2ykmb_ (2ykm B:)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (9 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)

6. Protein automated matches [190211] (7 species)
   not a true protein

7. Species Human immunodeficiency virus type 1 bh10 [TaxId:11678] [225820] (18 PDB entries)

8. Domain d2ykmb_: 2ykm B: [207659]
   Other proteins in same PDB: d2ykma2, d2ykma3
   automated match to d1hqeb_
   complexed with ca, ykn

Details for d2ykmb_

PDB Entry: 2ykm, 2.9 Å

PDB Description: crystal structure of hiv-1 reverse transcriptase (rt) in complex with a difluoromethylbenzoxazole (dfmb) pyrimidine thioether derivative, a non-nucleoside rt inhibitor (nnrti)

PDB Compounds: (B:) Reverse transcriptase/ribonuclease H

SCOPe Domain Sequences for d2ykmb_:

Sequence, based on SEQRES records:

>d2ykmb_ e.8.1.2 (B:) automated matches {Human immunodeficiency virus type 1 bh10 [TaxId: 11678]}
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyq

Sequence, based on observed residues (ATOM records):

>d2ykmb_ e.8.1.2 (B:) automated matches {Human immunodeficiency virus type 1 bh10 [TaxId: 11678]}
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdyelhpdkwtvqpivlpekdswt
vndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkep
vhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmtndvkqlteavqkitt
esiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq

Timeline for d2ykmb_:

• d2ykmb_ first appeared in SCOPe 2.03
  
• d2ykmb_ appears in SCOPe 2.07