Lineage for d2xyna_ (2xyn A:)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1929110Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1929111Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1929232Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1931583Protein automated matches [190091] (12 species)
    not a true protein
  7. 1931656Species Human (Homo sapiens) [TaxId:9606] [188447] (553 PDB entries)
  8. 1932288Domain d2xyna_: 2xyn A: [207438]
    automated match to d1m52b_
    complexed with cl, na, vx6

Details for d2xyna_

PDB Entry: 2xyn (more details), 2.81 Å

PDB Description: human abl2 in complex with aurora kinase inhibitor vx-680
PDB Compounds: (A:) Tyrosine-protein kinase ABL2

SCOPe Domain Sequences for d2xyna_:

Sequence, based on SEQRES records: (download)

>d2xyna_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kwemertditmkhklgggqygevyvgvwkkysltvavktlkedtmeveeflkeaavmkei
khpnlvqllgvctleppfyivteympygnlldylrecnreevtavvllymatqissamey
lekknfihrdlaarnclvgenhvvkvadfglsrlmtgdtytahagakfpikwtapeslay
ntfsiksdvwafgvllweiatygmspypgidlsqvydllekgyrmeqpegcppkvyelmr
acwkwspadrpsfaethqafetmfhd

Sequence, based on observed residues (ATOM records): (download)

>d2xyna_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kwemertditmkhklgggqygevyvgvwkkysltvavktldtmeveeflkeaavmkeikh
pnlvqllgvctleppfyivteympygnlldylrecnreevtavvllymatqissameyle
kknfihrdlaarnclvgenhvvkvadfglsrlmtgdtytahagakfpikwtapeslaynt
fsiksdvwafgvllweiatygmspypgidlsqvydllekgyrmeqpegcppkvyelmrac
wkwspadrpsfaethqafetmfhd

SCOPe Domain Coordinates for d2xyna_:

Click to download the PDB-style file with coordinates for d2xyna_.
(The format of our PDB-style files is described here.)

Timeline for d2xyna_: