SCOPe 2.08: Domain d2xu5a_: 2xu5 A:

Lineage for d2xu5a_ (2xu5 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.0: automated matches [191342] (1 protein)
   not a true family

6. Protein automated matches [190230] (23 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187072] (53 PDB entries)

8. Domain d2xu5a_: 2xu5 A: [207340]
   automated match to d3hd3b_
   complexed with flc, gol, xu5

Details for d2xu5a_

PDB Entry: 2xu5, 1.6 Å

PDB Description: cathepsin l with a nitrile inhibitor

PDB Compounds: (A:) Cathepsin L1

SCOPe Domain Sequences for d2xu5a_:

Sequence, based on SEQRES records:

>d2xu5a_ d.3.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
aprsvdwrekgyvtpvknqgqcgscwafsatgalegqmfrktgrlislseqnlvdcsgpq
gnegcngglmdyafqyvqdnggldseesypyeateesckynpkysvandtgfvdipkqek
almkavatvgpisvaidaghesflfykegiyfepdcssedmdhgvlvvgygfestesdnn
kywlvknswgeewgmggyvkmakdrrnhcgiasaasyptv

Sequence, based on observed residues (ATOM records):

>d2xu5a_ d.3.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
aprsvdwrekgyvtpvknqgqcgscwafsatgalegqmfrktgrlislseqnlvdcsgpq
gnegcngglmdyafqyvqdnggldseesypyeateesckynpkysvandtgfvdipkqek
almkavatvgpisvaidaghesflfykegiyfepdcssedmdhgvlvvgygfednnkywl
vknswgeewgmggyvkmakdrrnhcgiasaasyptv

Timeline for d2xu5a_:

• d2xu5a_ first appeared in SCOPe 2.03
  
• d2xu5a_ appears in SCOPe 2.07