Lineage for d2xp4a2 (2xp4 A:51-163)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2165782Fold d.26: FKBP-like [54533] (3 superfamilies)
    core: beta(2)-alpha-beta(2); antiparallel beta-sheet
  4. 2165783Superfamily d.26.1: FKBP-like [54534] (4 families) (S)
  5. 2165784Family d.26.1.1: FKBP immunophilin/proline isomerase [54535] (17 protein domains)
  6. 2165921Protein Mitotic rotamase PIN1, domain 2 [54547] (2 species)
    Domain 1 is a WW-domain
  7. 2165922Species Human (Homo sapiens) [TaxId:9606] [54548] (46 PDB entries)
  8. 2165931Domain d2xp4a2: 2xp4 A:51-163 [207294]
    Other proteins in same PDB: d2xp4a1
    automated match to d2itka2
    complexed with 12p, g14

Details for d2xp4a2

PDB Entry: 2xp4 (more details), 1.8 Å

PDB Description: discovery of cell-active phenyl-imidazole pin1 inhibitors by structure-guided fragment evolution
PDB Compounds: (A:) Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

SCOPe Domain Sequences for d2xp4a2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2xp4a2 d.26.1.1 (A:51-163) Mitotic rotamase PIN1, domain 2 {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2xp4a2:

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Timeline for d2xp4a2:

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Domains from same chain:
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