SCOPe 2.08: Domain d2x9va_: 2x9v A:

Lineage for d2x9va_ (2x9v A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.0: automated matches [191313] (1 protein)
   not a true family

6. Protein automated matches [190069] (319 species)
   not a true protein

7. Species Trypanosoma brucei [TaxId:5702] [226801] (37 PDB entries)

8. Domain d2x9va_: 2x9v A: [207164]
   automated match to d1p33a_
   complexed with act, nap, tmq

Details for d2x9va_

PDB Entry: 2x9v, 1.3 Å

PDB Description: High resolution structure of TbPTR1 with trimetrexate

PDB Compounds: (A:) pteridine reductase

SCOPe Domain Sequences for d2x9va_:

Sequence, based on SEQRES records:

>d2x9va_ c.2.1.0 (A:) automated matches {Trypanosoma brucei [TaxId: 5702]}
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvqgdhednsngktvetqva
eligtnaiapflltmsfaqrqkgtnpnctssnlsivnlcdamvdqpcmafslynmgkhal
vgltqsaalelapygirvngvapgvsllpvamgeeekdkwrrkvplgrreasaeqiadav
iflvsgsaqyitgsiikvdgglslvha

Sequence, based on observed residues (ATOM records):

>d2x9va_ c.2.1.0 (A:) automated matches {Trypanosoma brucei [TaxId: 5702]}
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvqgktvetqvaeligtnai
apflltmsfaqrqsnlsivnlcdamvdqpcmafslynmgkhalvgltqsaalelapygir
vngvapgvsllpvamgeeekdkwrrkvplgrreasaeqiadaviflvsgsaqyitgsiik
vdgglslvha

Timeline for d2x9va_:

• d2x9va_ first appeared in SCOPe 2.03
  
• d2x9va_ appears in SCOPe 2.07