SCOPe 2.05: Domain d2x9gc_: 2x9g C:

Lineage for d2x9gc_ (2x9g C:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.0: automated matches [191313] (1 protein)
   not a true family

6. Protein automated matches [190069] (203 species)
   not a true protein

7. Species Trypanosoma brucei [TaxId:5702] [226801] (26 PDB entries)

8. Domain d2x9gc_: 2x9g C: [207155]
   automated match to d1p33a_
   complexed with act, lya, nap

Details for d2x9gc_

PDB Entry: 2x9g, 1.1 Å

PDB Description: high resolution structure of tbptr1 in complex with pemetrexed

PDB Compounds: (C:) pteridine reductase

SCOPe Domain Sequences for d2x9gc_:

Sequence, based on SEQRES records:

>d2x9gc_ c.2.1.0 (C:) automated matches {Trypanosoma brucei [TaxId: 5702]}
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvqgdhednsngktvetqva
eligtnaiapflltmsfaqrqkgtnpnctssnlsivnlcdamvdqpcmafslynmgkhal
vgltqsaalelapygirvngvapgvsllpvamgeeekdkwrrkvplgrreasaeqiadav
iflvsgsaqyitgsiikvdgglslvha

Sequence, based on observed residues (ATOM records):

>d2x9gc_ c.2.1.0 (C:) automated matches {Trypanosoma brucei [TaxId: 5702]}
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvqgktvetqvaeligtnai
apflltmsfaqrqkgsnlsivnlcdamvdqpcmafslynmgkhalvgltqsaalelapyg
irvngvapgvsllpvamgeeekdkwrrkvplgrreasaeqiadaviflvsgsaqyitgsi
ikvdgglslvha

Timeline for d2x9gc_:

• d2x9gc_ first appeared in SCOPe 2.03
  
• d2x9gc_ appears in SCOPe 2.04
  
• d2x9gc_ appears in SCOPe 2.06
  
• d2x9gc_ appears in the current release, SCOPe 2.08