SCOPe 2.03: Domain d2x7fe_: 2x7f E:

Lineage for d2x7fe_ (2x7f E:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (18 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (314 PDB entries)

8. Domain d2x7fe_: 2x7f E: [207143]
   automated match to d3efla_
   complexed with 824, na

Details for d2x7fe_

PDB Entry: 2x7f, 2.8 Å

PDB Description: crystal structure of the kinase domain of human traf2- and nck- interacting kinase with wee1chk1 inhibitor

PDB Compounds: (E:) traf2 and nck-interacting protein kinase

SCOPe Domain Sequences for d2x7fe_:

Sequence, based on SEQRES records:

>d2x7fe_ d.144.1.0 (E:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dlsalrdpagifelvelvgngtygqvykgrhvktgqlaaikvmdvtgdeeeeikqeinml
kkyshhrniatyygafikknppgmddqlwlvmefcgagsvtdlikntkgntlkeewiayi
creilrglshlhqhkvihrdikgqnvlltenaevklvdfgvsaqldrtvgrrntfigtpy
wmapeviacdenpdatydfksdlwslgitaiemaegapplcdmhpmralfliprnpaprl
kskkwskkfqsfiesclvknhsqrpateqlmkhpfirdqpnerqvriqlkdhidrt

Sequence, based on observed residues (ATOM records):

>d2x7fe_ d.144.1.0 (E:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dlsalrdpagifelvelvggqvykgrhvktgqlaaikvmdvtgdeeeeikqeinmlkkys
hhrniatyygafikkddqlwlvmefcgagsvtdliknkeewiayicreilrglshlhqhk
vihrdikgqnvlltenaevklvdftpywmapevidfksdlwslgitaiemaegapplcdm
hpmralfliprnpaprlkskkwskkfqsfiesclvknhsqrpeqlmkhpfirdqpnerqv
riqlkdhidrt

Timeline for d2x7fe_:

• d2x7fe_ is new in SCOPe 2.03-stable
  
• d2x7fe_ appears in SCOPe 2.04
  
• d2x7fe_ appears in the current release, SCOPe 2.08