SCOPe 2.06: Domain d2x7fa_: 2x7f A:

Lineage for d2x7fa_ (2x7f A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (25 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (882 PDB entries)

8. Domain d2x7fa_: 2x7f A: [207139]
   automated match to d3efla_
   complexed with 824, na

Details for d2x7fa_

PDB Entry: 2x7f, 2.8 Å

PDB Description: crystal structure of the kinase domain of human traf2- and nck- interacting kinase with wee1chk1 inhibitor

PDB Compounds: (A:) traf2 and nck-interacting protein kinase

SCOPe Domain Sequences for d2x7fa_:

Sequence, based on SEQRES records:

>d2x7fa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lsalrdpagifelvelvgngtygqvykgrhvktgqlaaikvmdvtgdeeeeikqeinmlk
kyshhrniatyygafikknppgmddqlwlvmefcgagsvtdlikntkgntlkeewiayic
reilrglshlhqhkvihrdikgqnvlltenaevklvdfgvsaqldrtvgrrntfigtpyw
mapeviacdenpdatydfksdlwslgitaiemaegapplcdmhpmralfliprnpaprlk
skkwskkfqsfiesclvknhsqrpateqlmkhpfirdqpnerqvriqlkdhidrtkkkr

Sequence, based on observed residues (ATOM records):

>d2x7fa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lsalrdpagifelvelvgngtygqvykgrhvktgqlaaikvmdvtgdeeeeikqeinmlk
kyshhrniatyygafikkngmddqlwlvmefcgagsvtdlikntkgntlkeewiayicre
ilrglshlhqhkvihrdikgqnvlltenaevklvdfgvsagtpywmapeviaydfksdlw
slgitaiemaegapplcdmhpmralfliprnpaprlkskkwskkfqsfiesclvknhsqr
pateqlmkhpfirdqpnerqvriqlkdhidrtkkkr

Timeline for d2x7fa_:

• d2x7fa_ first appeared in SCOPe 2.03
  
• d2x7fa_ appears in SCOPe 2.05
  
• d2x7fa_ appears in SCOPe 2.07
  
• d2x7fa_ appears in the current release, SCOPe 2.08