SCOPe 2.05: Domain d2vwwa_: 2vww A:

Lineage for d2vwwa_ (2vww A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (21 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (615 PDB entries)

8. Domain d2vwwa_: 2vww A: [206508]
   automated match to d3pp0a_
   complexed with 7x2

Details for d2vwwa_

PDB Entry: 2vww, 1.9 Å

PDB Description: ephb4 kinase domain inhibitor complex

PDB Compounds: (A:) Ephrin type-B receptor 4

SCOPe Domain Sequences for d2vwwa_:

Sequence, based on SEQRES records:

>d2vwwa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eidvsyvkieevigagefgevcrgrlkapgkkescvaiktlkggyterqrreflseasim
gqfehpniirlegvvtnsmpvmiltefmengaldsflrlndgqftviqlvgmlrgiasgm
rylaemsyvhrdlaarnilvnsnlvckvsdfglsrfleenssdptetsslggkipirwta
peaiafrkftsasdawsygivmwevmsfgerpywdmsnqdvinaieqdyrlppppdcpts
lhqlmldcwqkdrnarprfpqvvsaldkmirnpaslkiv

Sequence, based on observed residues (ATOM records):

>d2vwwa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eidvsyvkieevigagefgevcrgrlkapgkkescvaiktlterqrreflseasimgqfe
hpniirlegvvtnsmpvmiltefmengaldsflrlndgqftviqlvgmlrgiasgmryla
emsyvhrdlaarnilvnsnlvckvsdfipirwtapeaiafrkftsasdawsygivmwevm
sfgerpywdmsnqdvinaieqdyrlppppdcptslhqlmldcwqkdrnarprfpqvvsal
dkmirnpaslkiv

Timeline for d2vwwa_:

• d2vwwa_ first appeared in SCOPe 2.03
  
• d2vwwa_ appears in SCOPe 2.04
  
• d2vwwa_ appears in SCOPe 2.06
  
• d2vwwa_ appears in the current release, SCOPe 2.08