SCOPe 2.08: Domain d2vurb2: 2vur B:179-495

Lineage for d2vurb2 (2vur B:179-495)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.8: (Trans)glycosidases [51445] (15 families)

5. Family c.1.8.10: alpha-D-glucuronidase/Hyaluronidase catalytic domain [82253] (4 proteins)
   Glycosyl hydrolase family 67, GH67; structurally related to GH20; contains extra C-terminal alpha-helical subdomain

6. Protein Hyaluronidase catalytic domain [141792] (1 species)

7. Species Clostridium perfringens [TaxId:1502] [141793] (9 PDB entries)
   Uniprot Q8XL08 179-495

8. Domain d2vurb2: 2vur B:179-495 [206492]
   Other proteins in same PDB: d2vura1, d2vura3, d2vurb1, d2vurb3
   automated match to d2cbia2
   complexed with so4, yx1

Details for d2vurb2

PDB Entry: 2vur, 2.2 Å

PDB Description: chemical dissection of the link between streptozotocin, o-glcnac and pancreatic cell death

PDB Compounds: (B:) O-GlcNAcase nagJ

SCOPe Domain Sequences for d2vurb2:

Sequence; same for both SEQRES and ATOM records:

>d2vurb2 c.1.8.10 (B:179-495) Hyaluronidase catalytic domain {Clostridium perfringens [TaxId: 1502]}
vsargivegfygtpwthqdrldqikfygenklntyiyapkddpyhrekwrepypesemqr
mqelinasaenkvdfvfgispgidirfdgdageedfnhlitkaeslydmgvrsfaiywdd
iqdksaakhaqvlnrfneefvkakgdvkplitvpteydtgamvsngqpraytrifaetvd
psievmwtgpgvvtneiplsdaqlisgiynrnmavwwnypvtdyfkgklalgpmhgldkg
lnqyvdfftvnpmehaelskisihtaadyswnmdnydydkawnraidmlygdlaedmkvf
anhstrmdnktwaksgr

Timeline for d2vurb2:

• d2vurb2 first appeared in SCOPe 2.03
  
• d2vurb2 appears in SCOPe 2.07