SCOPe 2.08: Domain d2vuka_: 2vuk A:

Lineage for d2vuka_ (2vuk A:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (9 superfamilies)
   sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold

4. Superfamily b.2.5: p53-like transcription factors [49417] (8 families)

5. Family b.2.5.2: p53 DNA-binding domain-like [81314] (3 proteins)

6. Protein automated matches [190198] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186941] (51 PDB entries)

8. Domain d2vuka_: 2vuk A: [206481]
   automated match to d2ahia_
   complexed with p83, zn; mutant

Details for d2vuka_

PDB Entry: 2vuk, 1.5 Å

PDB Description: structure of the p53 core domain mutant y220c bound to the stabilizing small-molecule drug phikan083

PDB Compounds: (A:) Cellular tumor antigen p53

SCOPe Domain Sequences for d2vuka_:

Sequence; same for both SEQRES and ATOM records:

>d2vuka_ b.2.5.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
svpsqktyqgsygfrlgflhsgtaksvtctyspalnklfcqlaktcpvqlwvdstpppgt
rvramaiykqsqhmtevvrrcphhercsdsdglappqhlirvegnlraeylddrntfrhs
vvvpceppevgsdcttihynymcysscmggmnrrpiltiitledssgnllgrdsfevrvc
acpgrdrrteeenlr

Timeline for d2vuka_:

• d2vuka_ first appeared in SCOPe 2.03
  
• d2vuka_ appears in SCOPe 2.07