Lineage for d1a8jl1 (1a8j L:1-111)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2739517Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2739518Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2739519Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 2741614Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
    VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family
  7. 2741646Species Human (Homo sapiens), cluster 4 [TaxId:9606] [88539] (23 PDB entries)
  8. 2741674Domain d1a8jl1: 1a8j L:1-111 [20597]
    Other proteins in same PDB: d1a8jh2, d1a8jl2
    part of the antibody MCG light chain dimer
    complexed with pme

Details for d1a8jl1

PDB Entry: 1a8j (more details), 2.7 Å

PDB Description: immunoglobulin lambda light chain dimer (mcg) complex with aspartame
PDB Compounds: (L:) immunoglobulin lambda light chain dimer (mcg)

SCOPe Domain Sequences for d1a8jl1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1a8jl1 b.1.1.1 (L:1-111) Immunoglobulin light chain lambda variable domain, VL-lambda {Human (Homo sapiens), cluster 4 [TaxId: 9606]}

SCOPe Domain Coordinates for d1a8jl1:

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Timeline for d1a8jl1:

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