Lineage for d2r3va2 (2r3v A:226-395)

  1. Root: SCOPe 2.03
  2. 1396887Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1413688Fold d.58: Ferredoxin-like [54861] (59 superfamilies)
    alpha+beta sandwich with antiparallel beta-sheet; (beta-alpha-beta)x2
  4. 1417584Superfamily d.58.26: GHMP Kinase, C-terminal domain [55060] (8 families) (S)
    common fold is elaborated with additional secondary structures
  5. 1417606Family d.58.26.3: Mevalonate kinase [75450] (1 protein)
  6. 1417607Protein Mevalonate kinase [75451] (3 species)
  7. 1417608Species Homo sapiens [TaxId:9606] [225476] (1 PDB entry)
  8. 1417609Domain d2r3va2: 2r3v A:226-395 [205956]
    Other proteins in same PDB: d2r3va1, d2r3vb1, d2r3vc1, d2r3vd1
    automated match to d1kvka2

Details for d2r3va2

PDB Entry: 2r3v (more details), 2.5 Å

PDB Description: The Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism
PDB Compounds: (A:) Mevalonate Kinase

SCOPe Domain Sequences for d2r3va2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2r3va2 d.58.26.3 (A:226-395) Mevalonate kinase {Homo sapiens}
rspalqilltntkvprntralvagvrnrllkfpeivaplltsidaislecervlgemgea
papeqylvleelidmnqhhlnalgvghasldqlcqvtrarglhskltgaggggcgitllk
pgleqpeveatkqaltscgfdcletsigapgvsihsatsldsrvqqaldg

SCOPe Domain Coordinates for d2r3va2:

Click to download the PDB-style file with coordinates for d2r3va2.
(The format of our PDB-style files is described here.)

Timeline for d2r3va2: