Lineage for d2qisa_ (2qis A:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2010547Fold a.128: Terpenoid synthases [48575] (1 superfamily)
    multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers
  4. 2010548Superfamily a.128.1: Terpenoid synthases [48576] (6 families) (S)
    duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J
  5. 2010549Family a.128.1.1: Isoprenyl diphosphate synthases [48577] (4 protein domains)
  6. 2010594Protein automated matches [190489] (5 species)
    not a true protein
  7. 2010595Species Human (Homo sapiens) [TaxId:9606] [187688] (78 PDB entries)
  8. 2010598Domain d2qisa_: 2qis A: [205820]
    automated match to d2f89f_
    complexed with mg, ris; mutant

Details for d2qisa_

PDB Entry: 2qis (more details), 1.8 Å

PDB Description: crystal structure of human farnesyl pyrophosphate synthase t210s mutant bound to risedronate
PDB Compounds: (A:) Farnesyl pyrophosphate synthetase

SCOPe Domain Sequences for d2qisa_:

Sequence, based on SEQRES records: (download)

>d2qisa_ a.128.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dvyaqekqdfvqhfsqivrvltedemghpeigdaiarlkevleynaiggkynrgltvvva
frelveprkqdadslqrawtvgwcvellqafflvaddimdssltrrgqicwyqkpgvgld
aindanlleaciyrllklycreqpyylnlielflqssyqteigqtldlltapqgnvdlvr
ftekryksivkyksafysfylpiaaamymagidgekehanakkillemgeffqiqddyld
lfgdpsvtgkigtdiqdnkcswlvvqclqratpeqyqilkenygqkeaekvarvkalyee
ldlpavflqyeedsyshimalieqyaaplppavflglarkiy

Sequence, based on observed residues (ATOM records): (download)

>d2qisa_ a.128.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dvyaqekqdfvqhfsqivrvltedehpeigdaiarlkevleynaiggkynrgltvvvafr
elveprkqdadslqrawtvgwcvellqafflvaddimdssltrrgqicwyqkpgvgldai
ndanlleaciyrllklycreqpyylnlielflqssyqteigqtldlltapqgnvdlvrft
ekryksivkyksafysfylpiaaamymagidgekehanakkillemgeffqiqddyldlf
gdpsvtgkigtdiqdnkcswlvvqclqratpeqyqilkenygqkeaekvarvkalyeeld
lpavflqyeedsyshimalieqyaaplppavflglarkiy

SCOPe Domain Coordinates for d2qisa_:

Click to download the PDB-style file with coordinates for d2qisa_.
(The format of our PDB-style files is described here.)

Timeline for d2qisa_: