SCOPe 2.06: Domain d2qi8a_: 2qi8 A:

Lineage for d2qi8a_ (2qi8 A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein c-src tyrosine kinase [56155] (2 species)
   PTK group; Src subfamily; non-membrane spanning protein tyrosine kinase

7. Species Chicken (Gallus gallus) [TaxId:9031] [56157] (48 PDB entries)

8. Domain d2qi8a_: 2qi8 A: [205818]
   automated match to d2gqgb_
   complexed with gol

Details for d2qi8a_

PDB Entry: 2qi8, 2.32 Å

PDB Description: crystal structure of drug resistant src kinase domain

PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase Src

SCOPe Domain Sequences for d2qi8a_:

Sequence, based on SEQRES records:

>d2qi8a_ d.144.1.7 (A:) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
kdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvmkk
lrheklvqlyavvseepiyivmeymskgclldflkgemgkylrlpqlvdmaaqiasgmay
vermnyvhrdlraanilvgenlvckvadfglarliedneytarqgakfpikwtapeaaly
grftiksdvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmc
qcwrkdpeerptfeylqafledyftstepqyqpgenl

Sequence, based on observed residues (ATOM records):

>d2qi8a_ d.144.1.7 (A:) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
kdaweipreslrlevklgqgcfgevwmgtwngttrvaiktleaflqeaqvmkklrheklv
qlyavvsepiyivmeymskgclldflkgemgkylrlpqlvdmaaqiasgmayvermnyvh
rdlraanilvgenlvckvadfglarlpikwtapeaalygrftiksdvwsfgilltelttk
grvpypgmvnrevldqvergyrmpcppecpeslhdlmcqcwrkdpeerptfeylqafled
yftstepqyqpgenl

Timeline for d2qi8a_:

• d2qi8a_ first appeared in SCOPe 2.03
  
• d2qi8a_ appears in SCOPe 2.05
  
• d2qi8a_ appears in SCOPe 2.07
  
• d2qi8a_ appears in the current release, SCOPe 2.08